IPHC / LSMBO – Strasbourg

The “Laboratoire de Spectrometrie de Masse Bio-Organique” (LSMBO : http://www.iphc.cnrs.fr/-Laboratoire-de-Spectrometrie-de-Masse-.html) belongs to the “Institut Plurisciplinaire Hubert Curien” (IPHC : http://www.iphc.cnrs.fr/) at the University of Strasbourg. The LSMBO is a 30 scientists team in the Analytical Sciences Department of the IPHC. It has a 25 years experience in the structural study of peptides and proteins by mass spectrometry which is now fully used in the field of proteomics. The laboratory is renowned for developing new methods in proteomic analysis and bioinformatics (https://msda.unistra.fr) as well as for the development of protein/protein interactions analysis by MS in large complexes. During the last 10 years, it has produced, through fruitful collaborations with biologists, more than 200 publications in international journals, covering the use of proteomics and protein/peptides analysis in mammalians, microorganisms, plants, in the context of fundamental biology or human diseases. Its research is characterized by pluridisciplinarity. The laboratory is involved in several national academic programs (ANR, INCa, Labex) and European FP7 programs such as NOTOX (http://www.notox-sb.eu/). Besides that, long term collaborations with several pharmaceutical companies cover topics such as full characterization of natural and/or recombinant proteins used in human therapy, toxicoproteomics, protein/drug interaction. The laboratory is equipped with more than 10 different mass spectrometers covering a wide diversity of geometries (ion traps, Q-TOFs, triple quadrupoles) from several manufacturers. It has an 18 years experience in MS data storage and archiving and has acquired an ISO 9001 certification in 2007. In 2013, more than 40 students have successfully prepared a Ph.D. in the laboratory.

 

Publications : http://www.iphc.cnrs.fr/-Publications-.html