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ProMetIS: open data and bioinformatics workflows for multi-omics phenotyping of cohorts

ProMetIS: open data and bioinformatics workflows for multi-omics phenotyping of cohorts

15 Fév 2022

The integration of multi-omics data is a major approach for the understanding of pathophysiological mechanisms and the discovery of biomarkers in health. However, few multi-omics data are publicly available to date. In a study recently published in the open data...
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

15 Déc 2021

A multi-omics analysis combined with artificial intelligence was conducted on a cohort of young patients (younger than 50 years) without major comorbidities including 47 “critical” (in the ICU under mechanical ventilation), 25 “non-critical” (in a non-critical care...
Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

1 Sep 2021

Host cell proteins (HCPs) are a major class of bioprocess-related impurities generated by the host organism and are generally present at low levels in purified biopharmaceutical products. The monitoring of these impurities is identified as an important critical...
The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity

The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity

22 Juin 2021

The small nucleolar particles of the C/D box snoRNP family participate in the biogenesis of ribosomes whose function is to decode the information carried by mRNA to synthesize proteins. Teams from the IMoPA (Nancy), IPHC/LSMBO/ProFI-Strasbourg (Strasbourg), GIM...
The Human Proteome Project reports 90% completion of the human proteome

The Human Proteome Project reports 90% completion of the human proteome

2 Nov 2020

Along with the publication of the “Blueprint” map of the Human Proteome in Nature Communications, JPR has just published a “virtual issue” of a selection of 60 publications on the human proteome celebrating 10 years of the Human Proteome...
Proline: an efficient and user-friendly software suite for large-scale proteomics

Proline: an efficient and user-friendly software suite for large-scale proteomics

9 Mar 2020

We are pleased and very proud to announce the publication of Proline in Bioinformatics. Motivation The proteomics field requires the production and publication of reliable mass spectrometry-based identification and quantification results. Although many tools or...
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Recent articles

  • ProlineSuite Version 2.2.0 : New Version to improve the PTMs oriented functionalities
  • ProMetIS: open data and bioinformatics workflows for multi-omics phenotyping of cohorts
  • Thematic course “Quantitative proteomics” 2022
  • Thematic course “Quantitative proteomics” 2021
  • Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

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