ProFI Proteomics
The Proteomics French Infrastructure is a national project set up to provide a unified service platform in proteomics studies.
It's open to both public and private collaborations.
Proteomics Services
Large scale protein identification and quantification
Current proteomics methods and instrumentation represent today a powerful tool to get new insights into complex biological systems.
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Targeted quantification
Targeted strategies have emerged ten years ago and are best suited when precise, ideally absolute, quantification of finite sets of proteins are required with highest sensitivity.
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Post-translational modifications: detection and quantification
Proteins are very often the subject of various post-translational modifications (PTMs) that can impact their association with other proteins and globally other biomolecules, their subcellular localization and their stability.
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Interactomics and protein complexes
Interactomics and protein complexes investigations are also based on our strategies and instrumentation for large-scale and targeted quantification.
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Characterization of intact proteins and complexes
The next frontiers in proteome research are the study of protein-ligand interactions, protein-peptide and protein-protein complexes, together with entire protein interaction networks by high-throughput methods.
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How to submit a request
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ProFI Proteomics Skills
Publications
On the international stage
National Networks
Tools and methods for the community
Last News
Structure of bacteriocins produced by the human gut symbiont revealed by Top-Down MS
In-vivo and in-vitro produced bacteriocin samples were analyzed by Top-Down MS to characterize the thioether bridge arrangement of a new class of sactipeptides produced by the gut symbiont. This original structure confers activity against pathogenic Clostridia and other multidrug-resistant strains and have no toxicity towards eukaryotic cells. This bacteriocin should be considered as a valuable candidate for drug development.
SMAP 2019 congress
The next SMAP meeting will take place in Strasbourg, France, from 16 to 19 of September. This congress is organized every two years by the French Society of Proteomics and the French Society of Mass Spectrometry and gather experts in Mass spectrometry and Proteomics...
Functional analysis and interpretation of proteomic data with ProteoRE (10 & 11/07/2019)
ProteoRE (Proteomics Research Environment) is a Galaxy-based platform for the functional analysis and the exploration of proteomics (and transcriptomics) data in biomedical research; it allows researchers to apply a large range of dedicated bioinformatics tools and data analysis workflows on their data, share their analyses with others, and enable tiers to repeat the same analysis while keeping tracks of the overall process. Currently, ProteoRE comprises 18 tools organized into five subsections for: i) data manipulation; ii) human and iii ) mouse species database annotation; iv) functional analysis; and v) pathway analysis along with graphical representations.
