Proteomics French Infrastructure - FR2048

ProFI Proteomics

EDyP

Exploring the Dynamics of Proteomes
Grenoble

LSMBO

BioOrganic Mass Spectrometry Laboratory
Strasbourg

ProTeoToul

Proteomics and Mass Spectrometry of Biomolecules
Toulouse

ProFI facilities are distributed over three sites in France

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The Proteomics French Infrastructure is a national project set up to provide a unified service platform in proteomics studies. It's open to both public and private collaborations.

Proteomics Services

make your work easier and faster!

Large scale protein identification and quantification

Current proteomics methods and instrumentation represent today a powerful tool to get new insights into complex biological systems.

Targeted quantification

Targeted strategies have emerged ten years ago and are best suited when precise, idealy absolute, quantification of finite sets of proteins are required with highest sensitivity.

Post-translational modifications: detection and quantification

Proteins are very often the subject of various post-tanslational modifications (PTMs) that can impact their association with other proteins and globally other biomolecules, their subcellular localization ans their stability.

Interactomics and protein complexes

Interactomics and protein complexes investigations are also based on our strategies and instrumentation for large scale and targeted quantification.

Characterization of intact proteins and complexes

The next frontiers in proteome research are the study of protein-ligand interactions, protein-peptide and protein-protein complexes, together with entire protein interaction networks by high-throughput methods.

Large scale protein identification and quantification

Current proteomics methods and instrumentation represent today a powerful tool to get new insights into complex biological systems.

Targeted quantification

Targeted strategies have emerged ten years ago and are best suited when precise, idealy absolute, quantification of finite sets of proteins are required with highest sensitivity.

Post-translational modifications: detection and quantification

Proteins are very often the subject of various post-tanslational modifications (PTMs) that can impact their association with other proteins and globally other biomolecules, their subcellular localization ans their stability.

Interactomics and protein complexes

Interactomics and protein complexes investigations are also based on our strategies and instrumentation for large scale and targeted quantification.

Characterization of intact proteins and complexes

The next frontiers in proteome research are the study of protein-ligand interactions, protein-peptide and protein-protein complexes, together with entire protein interaction networks by high-throughput methods.

Key Figures

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Projects 2022
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Samples 2022
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Proline Downloads
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Publications 2022

Last News

timsTOF SCP mass spectrometer installed at ProteoToul

timsTOF SCP mass spectrometer installed at ProteoToul

Thanks to the REACT-EU OCSSIGEN projet (Région Occitanie, FEDER funds), ProteoToul has acquired a high sensitivity timsTOF SCP mass spectrometer coupled to...

by Renaud Albigot13/04/2023
Online CIU of therapeutic mAB Glyco-Variants through Direct Hyphenation of CEX with Native Ion Mobility–MS

Online CIU of therapeutic mAB Glyco-Variants through Direct Hyphenation of CEX with Native Ion Mobility–MS

Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility–Mass Spectrometry Post-translational modifications...

by Alexandre Burel23/03/2023
ProlineSuite Version  2.2.0 : New Version to improve the PTMs oriented functionalities

ProlineSuite Version 2.2.0 : New Version to improve the PTMs oriented functionalities

This new release improves the PTMs oriented functionalities. The previous version introduced a clear distinction between modification sites and clusters of modifications...

by Véronique Dupierris07/02/2023

ProFI Proteomics Skills