ProFI Proteomics
The Proteomics French Infrastructure is a national project set up to provide a unified service platform in proteomics studies.
It's open to both public and private collaborations.
Proteomics Services
Large scale protein identification and quantification
Current proteomics methods and instrumentation represent today a powerful tool to get new insights into complex biological systems.
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Targeted quantification
Targeted strategies have emerged ten years ago and are best suited when precise, ideally absolute, quantification of finite sets of proteins are required with highest sensitivity.
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Post-translational modifications: detection and quantification
Proteins are very often the subject of various post-translational modifications (PTMs) that can impact their association with other proteins and globally other biomolecules, their subcellular localization and their stability.
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Interactomics and protein complexes
Interactomics and protein complexes investigations are also based on our strategies and instrumentation for large-scale and targeted quantification.
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Characterization of intact proteins and complexes
The next frontiers in proteome research are the study of protein-ligand interactions, protein-peptide and protein-protein complexes, together with entire protein interaction networks by high-throughput methods.
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How to submit a request
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ProFI Proteomics Skills
Publications
On the international stage
National Networks
Tools and methods for the community
Last News
ProlineSuite Version 2.1.2 : New FDR Control Procedure
This new version is an intermediate release which fixes some bugs and improves some features : see Release Note to get the full list of changes. The main new feature is the validation process. A method based on the Benjamini-Hochberg procedure to control the FDR is...
The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity
The small nucleolar particles of the C/D box snoRNP family participate in the biogenesis of ribosomes whose function is to decode the information carried by mRNA to synthesize proteins. Teams from the IMoPA (Nancy), IPHC/LSMBO/ProFI-Strasbourg (Strasbourg), GIM...
Inserm Workshop 262: Mass Spectrometry for Structural Biology (update)
This workshop will present the fundamental and applied aspects of Mass Spectrometry-based structural techniques, as well as data analysis procedures. State-of-the-art lectures will be given by experts in the field, destined to both non-MS and MS specialists. Program...
