ProFI is actively implicated in the C-HPP initiative (Chromosome-centric Human Proteome Project) managed by HUPO. This very ambitious project aims to systematically identify all the protein forms present in all tissues, cell type and fluids of the human body through the massive use of proteomics. It combines the efforts of over 25 national networks worldwide. The work of cataloguing the proteins expressed was organized by chromosome, and France was allocated responsibility for chromosome 14. This work was carried out in the context of a close collaboration with Swiss teams (coordinator Lydie Lane; chromosome 2). After a first publication (Carapito et al., 2015), our activity within C-HPP was followed by a new large study analysing proteins expressed in the human testis and sperm (coll C. Pineau; Vandenbrouck et al., 2016  ; Carapito et al., 2017). ProFI contacts: Yves Vandenbrouck, Christine Carapito

HUPO Bioinformatics Hub. Members of ProFI were at the initiative of the Bioinformatic Hub which is now a recurrent event at HUPO since 2015 and participate to the management of this gathering. The Bioinformatics Hub is a place where bioinformaticians gather together with three aims:

1. to provide their advice, knowledge, and support to anyone with a relevant question;
2. to discuss current issues and challenges in proteomics informatics with the entire community;
3. to work on interesting, synergistic projects and to freely exchange tools, algorithms and know-how with each other, across all labs, seniorities and levels of experience. ProFI contacts: Yves Vandenbrouck, David Bouyssié